What factors increase the risk for developing hospital-acquired pneumonia (HAP)?

Updated: Jul 30, 2018
  • Author: Burke A Cunha, MD; Chief Editor: John L Brusch, MD, FACP  more...
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Answer

Answer

The stomach appears to be an important reservoir of gram-negative bacilli that can ascend and colonize the respiratory tract. A prospective observational study found that patients who used acid-suppressive medications were more likely to develop hospital-acquired pneumonia (HAP) than were patients who did not (5% vs 2%). The risk for pneumonia was significantly increased with proton pump inhibitors, but not with histamine 2–blocking agents. [7]


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