Which antimicrobials are used in empiric monotherapy regimens for the treatment of bacterial sepsis?

Updated: Feb 05, 2019
  • Author: Amber Mahmood Bokhari, MBBS; Chief Editor: Michael Stuart Bronze, MD  more...
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Answer

Appropriate antimicrobial therapy depends on adequate coverage of the bacteria associated with the specific organ or organ system associated with the infection. [46, 29, 47, 28, 30] Agents suitable for empiric monotherapy regimens (depending on the source and underlying microbiology of the sepsis because the agent must be able to cover all of the likely pathogens) may include the following:

  • Imipenem
  • Meropenem
  • Tigecycline
  • Piperacillin-tazobactam
  • Ampicillin-sulbactam
  • Moxifloxacin

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