How is community-acquired pneumonia (CAP) treated in hospitalized patients?

Updated: Oct 31, 2019
  • Author: Stephanie L Baer, MD; Chief Editor: Michael Stuart Bronze, MD  more...
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Answer

Answer

For hospitalized patients, therapy consists of the following:

  • Beta-lactams (ampicillin/sulbactam 1.5-3 g every 6 hours, ceftriaxone 1-2 g daily, cefotaxime 1-2 g every 8 hours, or ceftaroline 600 mg every 12 hours) plus a macrolide OR
  • Respiratory fluoroquinolone OR
  • If macrolides and fluoroquinolones are contraindicated: beta-lactam as above plus doxycycline

Recent studies have failed to show that the use of a beta-lactam alone is noninferior to a beta-lactam/macrolide combination for time to clinical stability and other safety parameters in hospitalized patients. [70]


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