Which medications in the drug class Analgesics/Antipyretics are used in the treatment of West Nile Virus (WNV) Infection and Encephalitis (WNE)?

Updated: Apr 05, 2021
  • Author: David J Cennimo, MD, FAAP, FACP, AAHIVS; Chief Editor: Michael Stuart Bronze, MD  more...
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Answer

Analgesics/Antipyretics

These agents are helpful in relieving the associated lethargy, malaise, and fever associated with the disease.

Acetaminophen (Acephen, FeverAll, Tylenol)

Acetaminophen inhibits the action of endogenous pyrogens on heat-regulating centers; it reduces fever by a direct action on the hypothalamic heat-regulating centers, which, in turn, increases the dissipation of body heat via sweating and vasodilation. It is effective in relieving mild to moderate acute pain; however, it has no peripheral anti-inflammatory effects. Acetaminophen may be preferred in elderly patients because of fewer GI and renal side effects.


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