What is the treatment for bacterial meningitis in the setting of HIV infection?

Updated: Jul 16, 2019
  • Author: Rodrigo Hasbun, MD, MPH; Chief Editor: Michael Stuart Bronze, MD  more...
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Answer

In HIV-infected patients, if an ED workup does not identify a pathogen, serum and CSF samples should be drawn for cryptococcal antigen testing. Empiric treatment should proceed as in adults older than 50 years (pending results of all blood and CSF tests) to cover the bacterial pathogens, particularly S pneumoniae and L monocytogenes, for which this patient population is most at risk. (See Meningitis in HIV.)


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