What is the role of culture from cerebrospinal fluid (CSF) in viral meningitis?

Updated: Jul 16, 2019
  • Author: Rodrigo Hasbun, MD, MPH; Chief Editor: Michael Stuart Bronze, MD  more...
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Answer

Isolation of viruses from the CSF has a sensitivity of 65-70% for enteroviruses. Alternatively, isolation of enteroviruses from throat and stool viral cultures may also indirectly implicate enterovirus as the cause of the meningitis. Culture of mumps virus from the CSF has a low sensitivity (30-50%). LCM virus may be cultured in blood early in the disease or in urine at a later stage.


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