What are risk factors for developing meningitis caused by gram-negative bacilli (Enterobacteriaceae)?

Updated: Jul 16, 2019
  • Author: Rodrigo Hasbun, MD, MPH; Chief Editor: Michael Stuart Bronze, MD  more...
  • Print

Gram-negative bacilli can cause meningitis in certain groups of patients. E coli is a common agent of meningitis among neonates. Other predisposing risk factors for meningitis associated with gram-negative bacilli include the following:

  • Neurosurgical procedures or intracranial manipulation

  • Old age

  • Immunosuppression

  • High-grade gram-negative bacillary bacteremia

  • Disseminated strongyloidiasis

Disseminated strongyloidiasis has been reported as a classic cause of gram-negative bacillary bacteremia, as a result of the translocation of gut microflora with the Strongyloides stercoralis larvae during hyperinfection syndrome.

Did this answer your question?
Additional feedback? (Optional)
Thank you for your feedback!