Which medications in the drug class Tetracyclines are used in the treatment of Acute Sinusitis?

Updated: Mar 01, 2018
  • Author: Itzhak Brook, MD, MSc; Chief Editor: Michael Stuart Bronze, MD  more...
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Answer

Tetracyclines

Tetracyclines inhibit protein synthesis and, thus, bacterial growth by binding to 30S and possibly 50S ribosomal subunits of susceptible bacteria. They may block dissociation of peptidyl t-RNA from ribosomes, causing RNA-dependent protein synthesis to arrest.

Doxycycline (Doryx, Adoxa, Monodox, Vibramycin)

Doxycycline has broad-spectrum activity and is a synthetically derived bacteriostatic antibiotic in the tetracycline class. Doxycycline inhibits protein synthesis, and thus bacterial growth, by binding to 30S and possibly 50S ribosomal subunits of susceptible bacteria.


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