How often does H influenzae cause acute bacterial rhinosinusitis (sinus infection)?

Updated: Mar 01, 2018
  • Author: Itzhak Brook, MD, MSc; Chief Editor: Michael Stuart Bronze, MD  more...
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Answer

H influenzae are gram-negative, facultatively anaerobic bacilli. H influenzae type B was a leading cause of meningitis until the widespread use of the vaccine. Nontypeable strains of H influenzae are responsible for 22-35% of acute bacterial rhinosinusitis cases in adults. Beta-lactamase production is the mechanism of antimicrobial resistance for this organism. Of isolates from the paranasal sinus, 32.7% were found to be beta-lactamase–positive for H influenzae; other reports suggest a rate of 44%.


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