What are the options for first-line antibiotic therapy for acute sinusitis (sinus infection)?

Updated: Mar 01, 2018
  • Author: Itzhak Brook, MD, MSc; Chief Editor: Michael Stuart Bronze, MD  more...
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Antibiotic treatment is usually given for 14 days. Usual first-line therapy is with one of the following:

  • Amoxicillin, at double the usual dose (80-90 mg/kg/d), especially in areas with known Streptococcus pneumoniae resistance

  • Clarithromycin

  • Azithromycin

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