Which medications in the drug class Immune Globulins are used in the treatment of Varicella-Zoster Virus (VZV)?

Updated: Feb 15, 2019
  • Author: Wayne E Anderson, DO, FAHS, FAAN; Chief Editor: Pranatharthi Haran Chandrasekar, MBBS, MD  more...
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Answer

Immune Globulins

The specific immune globulin with IgG varicella zoster antibodies provides passive immunization for susceptible individuals when administered within 10 days (ideally within 96 hours) of exposure.

Varicella zoster immune globulin, human (VariZIG)

Varicella zoster immune globulin (VZIG) contains immunoglobulin G (IgG) varicella-zoster antibodies. It provides passive immunization to exposed individuals at high risk of complications from varicella. High- risk groups include immunocompromised children and adults, newborns of mothers with varicella shortly before or after delivery, premature infants, infants < 1 year, adults without evidence of immunity, and pregnant women. Administer by deep IM injection, preferably in deltoid muscle. For neonates or infants, administer IM in anterolateral aspect of thigh.


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