Which antibiotic regimens are indicated to prevent urinary tract infection (UTI) in males undergoing urologic procedures?

Updated: Aug 27, 2019
  • Author: John L Brusch, MD, FACP; Chief Editor: Michael Stuart Bronze, MD  more...
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Answer

Regimens for high-risk patients include ampicillin (or vancomycin) plus gentamicin. Ampicillin is given as 2000mg IM or IV within 30 minutes of starting the procedure; 6 hours later, 1000mg of ampicillin (or amoxicillin PO) is given once. Gentamicin is dosed at 1.5 mg/kg IV or IM (not to exceed 120mg) and is given only once, with the first dose of ampicillin. For patients allergic to ampicillin, 1000mg of vancomycin is given IV over 1-2 hours only once; it should be completed within 30 minutes of starting the procedure.


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