Why is trimethoprim-sulfamethoxazole avoided in the treatment of prostatitis?

Updated: Aug 27, 2019
  • Author: John L Brusch, MD, FACP; Chief Editor: Michael Stuart Bronze, MD  more...
  • Print
Answer

The combination antimicrobial TMP-SMZ should generally be avoided. Only the TMP penetrates the prostate, and its sulfa component may be nephrotoxic. Generally, if TMP is not available because of formulary reasons, resort to quinolone or tetracycline.


Did this answer your question?
Additional feedback? (Optional)
Thank you for your feedback!