What is the prevalence antibiotic resistance in the treatment of urinary tract infection (UTI) in men?

Updated: Aug 27, 2019
  • Author: John L Brusch, MD, FACP; Chief Editor: Michael Stuart Bronze, MD  more...
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Answer

Unfortunately, the prevalence of uropathogens resistant to TMP-SMZ, nitrofurantoin, and first-generation cephalosporins has continued to rise. There are data that suggest overall resistance to TMP-SMZ is approximately 25% (range, 10-45%), based on the area of the country, and resistance to nitrofurantoin is slightly higher. Although studies have indicated that resistance to fluoroquinolones has been acceptably low, more recent microbiologic data suggest that fluoroquinolone resistance, particularly on the West Coast, may be an increasing problem. Despite these concerns, fluoroquinolones remain the preferred initial drug therapy. [16]


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