What are the infectious and noninfectious causes of pyuria in males?

Updated: Jan 02, 2020
  • Author: John L Brusch, MD, FACP; Chief Editor: Michael Stuart Bronze, MD  more...
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The differential diagnoses for infectious causes of sterile pyuria include perinephric abscess, urethral syndrome, chronic prostatitis, renal tuberculosis, and fungal infections of the urinary tract, including C neoformans and Coccidioides immitis.

Noninfectious causes of pyuria include uric acid and hypercalcemic nephropathy, lithium and heavy metal toxicity, sarcoidosis, interstitial cystitis, polycystic kidney disease, genitourinary malignancy, and renal transplant rejection.

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