What is the etiology and pathophysiology of orchitis?

Updated: Aug 27, 2019
  • Author: John L Brusch, MD, FACP; Chief Editor: Michael Stuart Bronze, MD  more...
  • Print
Answer

Because of the widespread use of mumps vaccination, orchitis is no longer a common infection in the United States. Orchitis is one of the few genitourinary infections to result from a viral pathogen.

Mumps orchitis occurs in 18% of postpubertal boys infected with the mumps virus. Other viruses that can cause the disease include coxsackie B, mononucleosis, and varicella. Unlike the majority of genitourinary infections, viral particles are spread to the testicle by the hematogenous route. Granulomatous orchitis is rare and results from hematogenous dissemination of tuberculosis, fungi, and actinomycosis.


Did this answer your question?
Additional feedback? (Optional)
Thank you for your feedback!