What are genitourinary complications of typhoid fever (enteric fever)?

Updated: Aug 19, 2019
  • Author: John L Brusch, MD, FACP; Chief Editor: Michael Stuart Bronze, MD  more...
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Genitourinary manifestations may include the following:

  • Approximately 25% of patients with typhoid fever excrete S typhi in their urine at some point during their illness.

  • Immune complex glomerulitis [80] and proteinuria have been reported, and IgM, C3 antigen, and S typhi antigen can be demonstrated in the glomerular capillary wall.

  • Nephritic syndrome may complicate chronic S typhi bacteremia associated with urinary schistosomiasis.

  • Nephrotic syndrome may occur transiently in patients with glucose-6-phosphate dehydrogenase deficiency.

  • Cystitis: Typhoid cystitis is very rare. Retention of urine in the typhoid state may facilitate infection with coliforms or other contaminants.

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