What is in the Vi capsular polysaccharide (ViCPS) antigen vaccine used in the prevention of typhoid fever (enteric fever)?

Updated: Aug 19, 2019
  • Author: John L Brusch, MD, FACP; Chief Editor: Michael Stuart Bronze, MD  more...
  • Print

Vi capsular polysaccharide antigen vaccine is composed of purified Vi antigen, the capsular polysaccharide elaborated by S typhi isolated from blood cultures. The Vi antigen is absent in S paratyphi A, but this vaccine does provide some in vitro immunogenicity against S paratyphi A. This may be due to trace amounts of other, common antigens in the preparation. [72]

Did this answer your question?
Additional feedback? (Optional)
Thank you for your feedback!