When should typhoid fever (enteric fever) vaccine be given to individuals traveling to an endemic area?

Updated: Aug 19, 2019
  • Author: John L Brusch, MD, FACP; Chief Editor: Michael Stuart Bronze, MD  more...
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Answer

Travelers should be vaccinated at least one week prior to departing for an endemic area. Because typhoid vaccines lose effectiveness after several years, consultation with a specialist in travel medicine is advised if the individual is traveling several years after vaccination. In addition, clinicians should warn travelers to consume only safe foods and beverages, because typhoid vaccines offer only moderate protection, and large inocula of S t yphi can overcome vaccine-induced protection.


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