What is the efficacy of metronidazole in the treatment of trichomoniasis?

Updated: Jan 02, 2020
  • Author: Darvin Scott Smith, MD, MSc, DTM&H; Chief Editor: Michael Stuart Bronze, MD  more...
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Answer

Treatment failure with single-dose metronidazole therapy increased from 0.4% to 3.5% between 1999 and 2002. [121] Reports now describe resistance to metronidazole approaching 5%-10%. If standard treatment with either single-dose or multidose therapy fails, a regimen of 2 g of oral metronidazole or tinidazole for 5 days may be considered. [11]

Metronidazole gel is effective in less than 50% of trichomoniasis cases and is not recommended to treat trichomoniasis. [122]


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