What are the treatment options for drug-resistant trichomoniasis?

Updated: Jan 02, 2020
  • Author: Darvin Scott Smith, MD, MSc, DTM&H; Chief Editor: Michael Stuart Bronze, MD  more...
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Despite the widespread use of nitroimidazoles in the treatment of trichomoniasis, resistance to these drugs is rare and is typically solved by increasing the dose or switching to another nitroimidazole. [1] The CDC has reported incidents of trichomoniasis resistant to metronidazole that were susceptible to tinidazole. [117, 118] When standard treatment regimens fail, a regimen of 2 g of oral metronidazole or tinidazole for 5 days may be considered. [57] Inpatient intravenous (IV) therapy may be indicated when resistance is present.

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