How is the APTIMA Trichomonas vaginalis ATV Assay used in the diagnosis of trichomoniasis?

Updated: Jan 02, 2020
  • Author: Darvin Scott Smith, MD, MSc, DTM&H; Chief Editor: Michael Stuart Bronze, MD  more...
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Answer

The APTIMA Trichomonas vaginalis Assay (Gen-Probe, San Diego, Calif) uses nucleic acid hybridization technology to detect the presence of T vaginalis. [57, 82] Sensitivity is 74%-98%, and specificity is 87%-98%. [38] One study reported decreased sensitivity for tests performed on first-void urine specimens in male patients. [79] The sample is run on a proprietary processing system capable of running about 1,000 samples per day. Expected turnaround time is about 1-2 days. Currently, the APTIMA Combo2 assay is FDA-approved for the diagnosis of chlamydia and gonorrhea, so laboratories using this technology may wish to add the T vaginalis assay to their existing technology.


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