How is the OSOM Trichomonas Rapid Test used to diagnose trichomoniasis?

Updated: Jan 02, 2020
  • Author: Darvin Scott Smith, MD, MSc, DTM&H; Chief Editor: Michael Stuart Bronze, MD  more...
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Answer

The OSOM Trichomonas Rapid Test uses color immunochromatographic “dipstick” technology with murine monoclonal antibodies. Results are read within 10 minutes. Freezing and transportation of specimens do not appreciably alter the test results. In a comparison with a composite reference standard of wet mount microscopy and culture, Huppert et al found the sensitivity of the OSOM test to be 83.3% and the specificity 98.8%. [85] A second study by Huppert et al found a sensitivity of 82% in comparison with a composite reference standard of wet mount, culture, rapid antigen testing, and polymerase chain reaction (PCR). [86] A third study compared the OSOM test to a composite reference standard for which a positive sample was defined as one that was positive by any combination of wet mount, Aptima ATV assay, or OSOM test. The prevalence of infection in the population tested was low, at 2%. The sensitivity was 94.7%, and the specificity was 100%. [87]


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