Which medications in the drug class Cycloplegics/Mydriatics are used in the treatment of Toxoplasmosis?

Updated: Mar 08, 2019
  • Author: Murat Hökelek, MD, PhD; Chief Editor: Michael Stuart Bronze, MD  more...
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Answer

Cycloplegics/Mydriatics

As in any eye with uveitis, posterior synechiae often form if a pupil is not mobilized. Anticholinergic agents, such as cyclopentolate, atropine, and homatropine, block the sphincter muscle of the iris and the muscle in the ciliary body that is responsible for accommodation to produce mydriasis and paralysis of accommodation.

Cyclopentolate 0.5%, 1%, 2% (AK-Pentolate, Cyclogyl, Cylate)

This agent prevents the muscle of the ciliary body and the sphincter muscle of the iris from responding to cholinergic stimulation. It induces mydriasis in 30-60 minutes and cycloplegia in 25-75 minutes. Infants should not be given concentrations of more than 0.5%.


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