What is the role of ultrasonography in the workup of congenital toxoplasmosis?

Updated: Mar 08, 2019
  • Author: Murat Hökelek, MD, PhD; Chief Editor: Michael Stuart Bronze, MD  more...
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Ultrasonographic diagnosis of congenital toxoplasmosis in a fetus is available at 20-24 weeks' gestation. Fetal or neonatal ultrasonography can be useful in cases of known or suspected maternal acute infection and transplacental infection. Findings are generally nonspecific but include ventriculomegaly and CNS calcifications, particularly in the basal ganglia.

Moreover, clinicians should consider a diagnosis of toxoplasmosis in pregnant women with clinical symptoms and signs such as cervical lymphadenopathy and consider CT scanning in fetuses with ultrasonographic abnormalities compatible with TORCH infections (an acronym for toxoplasmosis, other [syphilis, varicella-zoster, parvovirus B19], rubella, cytomegalovirus, herpes infections). [53]

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