What are the possible comorbidities of toxoplasmosis?

Updated: Mar 08, 2019
  • Author: Murat Hökelek, MD, PhD; Chief Editor: Michael Stuart Bronze, MD  more...
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Answer

Recent investigations have suggested that chronic toxoplasmosis may play several roles in the etiology of different mental disorders. [23]

Numerous clinical studies have evaluated the prevalence of anti-Toxoplasma antibodies in patients with schizophrenia and other forms of severe psychiatric disorders. The most probable mechanism by which T gondii could cause schizophrenia is by affecting neurotransmitters in brain areas known to be involved in schizophrenia. [24, 25] According to these studies, bradyzoites of T gondii affect dopamine and other neurotransmitters in rodents and humans. A few studies have also investigated the association between T gondii infection and Parkinson and Alzheimer diseases. [26, 27]


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