Which genotypic manifestations are associated with recurrence of toxoplasmic retinochoroiditis?

Updated: Mar 08, 2019
  • Author: Murat Hökelek, MD, PhD; Chief Editor: Michael Stuart Bronze, MD  more...
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Answer

It appears that IL-1 gene polymorphisms, in particular genotypes that are related with a high production of IL-1a, may be associated with recurrence of toxoplasmic retinochoroiditis. [13] IL-10 polymorphisms associated with a low production of IL-10 also appear to be associated with the occurrence of toxoplasmic retinochoroiditis. [14] In contrast, tumor necrosis factor (TNF)–alpha gene polymorphism has not been found to be associated with the occurrence or recurrence of toxoplasmic retinochoroiditis. [15]


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