What is the role of sucrose-depleted IV immune globulin (IVIg) in the treatment of toxic epidermal necrolysis (TEN)?

Updated: Jul 01, 2021
  • Author: Samantha P Jellinek-Cohen, PharmD, BCPS (AQ-ID); Chief Editor: Michael Stuart Bronze, MD  more...
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Answer

Sucrose-depleted IVIg 1 g/kg/d (infused over 4 h) for 3 days may be beneficial if started within 48-72 hours of bulla onset. If more than 72 hours have elapsed since the onset of bulla but TEN is still actively progressing, with new lesions, IVIg may still be useful.


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