Which histological findings are characteristic of toxic epidermal necrolysis (TEN)?

Updated: Jul 01, 2021
  • Author: Samantha P Jellinek-Cohen, PharmD, BCPS (AQ-ID); Chief Editor: Michael Stuart Bronze, MD  more...
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Answer

Histologically, TEN is characterized by full-thickness epidermal necrosis with little evidence of epidermal or dermal inflammation. Epidermal detachment and sloughing may be evident. Satellite cell necrosis may be visible early, progressing to extensive eosinophilic necrosis.


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