How are necrotic keratinocytes characterized in toxic epidermal necrolysis (TEN)?

Updated: Jul 01, 2021
  • Author: Samantha P Jellinek-Cohen, PharmD, BCPS (AQ-ID); Chief Editor: Michael Stuart Bronze, MD  more...
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Answer

Necrotic keratinocytes with full-thickness epithelial necrosis and detachment is consistent with the diagnosis of TEN. Perivascular and scattered lymphocytic infiltration of the dermis is sometimes demonstrated, although the underlying dermis is not greatly altered.


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