What is the relationship of erythema multiforme major (EMM) to toxic epidermal necrolysis (TEN)?

Updated: Jul 01, 2021
  • Author: Samantha P Jellinek-Cohen, PharmD, BCPS (AQ-ID); Chief Editor: Michael Stuart Bronze, MD  more...
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Answer

Toxic epidermal necrolysis (TEN) and Stevens-Johnson syndrome (SJS) are considered to be a single disease entity differing in severity. There is debate whether TEN and SJS are part of a spectrum of disorders including erythema multiforme major (EMM); however, it is widely accepted that SJS and TEN are distinct entities differing in etiology, clinical manifestations, histopathology, treatment, and prognosis.


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