Which NSAIDS cause toxic epidermal necrolysis (TEN)?

Updated: Jul 01, 2021
  • Author: Samantha P Jellinek-Cohen, PharmD, BCPS (AQ-ID); Chief Editor: Michael Stuart Bronze, MD  more...
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Answer

NSAIDs associated with TEN include the following:

  • Phenylbutazone and oxybutazone - Implicated most commonly, although they are no longer available in the United States

  • Oxicams (eg, piroxicam, tenoxicam) - Implicated more often than other NSAIDs

  • Ibuprofen

  • Indomethacin

  • Sulindac

  • Tolmetin


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