Which anticonvulsants cause toxic epidermal necrolysis (TEN)?

Updated: Jul 01, 2021
  • Author: Samantha P Jellinek-Cohen, PharmD, BCPS (AQ-ID); Chief Editor: Michael Stuart Bronze, MD  more...
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Answer

Anticonvulsants associated with TEN include the following:

  • Phenobarbital
  • Phenytoin20
  • Carbamazepine
  • Valproic acid
  • Lamotrigine

TEN in patients taking anticonvulsants has most often been reported within 2 months of starting the drug. However, some cases associated with long-term use have been reported.


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