Which antibacterial drugs cause toxic epidermal necrolysis (TEN)?

Updated: Jul 01, 2021
  • Author: Samantha P Jellinek-Cohen, PharmD, BCPS (AQ-ID); Chief Editor: Michael Stuart Bronze, MD  more...
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Answer

Antibacterial drugs associated with TEN include the following:

  • Sulfonamides (4.5 cases per million users per week)
  • Chloramphenicol
  • Macrolides (eg, azithromycin, clarithromycin, erythromycin, telithromycin)17
  • Penicillins
  • Quinolones (eg, ciprofloxacin,18 trovafloxacin19)

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