What are the dermatologic, neurologic, vascular, renal, and musculoskeletal complications in strongyloidiasis?

Updated: Jun 20, 2019
  • Author: Pranatharthi Haran Chandrasekar, MBBS, MD; Chief Editor: Michael Stuart Bronze, MD  more...
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Dermatologic complications include larva currens, purpura of the trunk and proximal extremities, and chronic urticaria.

Neurologic complications include meningitis due to enteric bacteria and brain abscess.

Vascular complications include hyperinfection syndrome presenting as bacteremia (occasionally recurrent) due to enteric microorganisms (eg, Escherichia coli, Klebsiella pneumoniae, Enterococcus species including vancomycin-resistant E faecium, Streptococcus bovis).

Renal complications can rarely include nephrotic syndrome [44] (eg, minimal-change nephrotic syndrome [45] ). Resolution of the proteinuria occurs after administration of antihelmintic therapy with ivermectin. Incidence of nephrotic syndrome in children in the developing world is increased in those with underlying strongyloidiasis. [46] In addition, the syndrome of inappropriate antidiuretic hormone (SIADH) has been observed in patients with severe Strongyloides infection. [47]

Rarely, a musculoskeletal complication such as reactive arthritis may occur.

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