Which histologic findings suggest group A streptococcal (GAS) infection?

Updated: Sep 07, 2018
  • Author: Zartash Zafar Khan, MD, FACP; Chief Editor: Pranatharthi Haran Chandrasekar, MBBS, MD  more...
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Answer

Gram stain of tissue shows gram-positive cocci in chains or clusters. Tissue removed for diagnostic or therapeutic measures may show inflammation with polymorph neutrophil infiltration, cytotoxic effects, and/or extensive necrosis. In case of PSGN, immune complex deposition is observed on glomerular basement membrane. (See the image below.)

Group A Streptococcus on Gram stain of blood isola Group A Streptococcus on Gram stain of blood isolated from a patient who developed toxic shock syndrome.

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