Which ancillary lab tests may be useful in the diagnosis and management of group A streptococcal (GAS) infections?

Updated: Sep 07, 2018
  • Author: Zartash Zafar Khan, MD, FACP; Chief Editor: Pranatharthi Haran Chandrasekar, MBBS, MD  more...
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Answer

Serologic assays (antistreptococcal antibodies) are a potentially useful adjunct for diagnosis. Other ancillary laboratory tests—eg, complete blood count (CBC), white blood cell (WBC) count, erythrocyte sedimentation rate, and C-reactive protein—may also be useful, depending on the manifestations of disease under consideration.

Other tests, depending on disease syndrome, can be very diverse in nature. For example, a histopathologic analysis of skin biopsy specimens, which may need to be analyzed intraoperatively, is warranted in cases of suspected necrotizing fasciitis. Calculation of creatinine clearance may be valuable in assessing the extent of renal dysfunction for nephritis.


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