What are the diagnostic criteria for streptococcal toxic shock syndrome (STSS)?

Updated: Sep 07, 2018
  • Author: Zartash Zafar Khan, MD, FACP; Chief Editor: Pranatharthi Haran Chandrasekar, MBBS, MD  more...
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Answer

Criteria proposed by the Working Group on Severe Streptococcal Infections for the diagnosis of streptococcal toxic shock are outlined as follows [27] :

  • Isolation of group A Streptococcus - From a sterile site or from a nonsterile body site

  • Clinical signs of severity (2 or more of the following clinical and laboratory abnormalities are required) - Renal impairment, coagulopathy, liver abnormalities, acute respiratory distress, extensive tissue necrosis (necrotizing fasciitis), erythematous rash

  • Definite case - Isolation of group A Streptococcus from a sterile site plus compatible clinical signs

  • Probable case - Isolation of group A Streptococcus from a nonsterile body site plus compatible clinical signs


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