What is a major risk factor for the development of group A streptococcal (GAS) necrotizing fasciitis (streptococcal gangrene/fasciitis)?

Updated: Sep 07, 2018
  • Author: Zartash Zafar Khan, MD, FACP; Chief Editor: Pranatharthi Haran Chandrasekar, MBBS, MD  more...
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Answer

A major risk factor for the development of streptococcal necrotizing fasciitis is a history of recent varicella-zoster virus (VZV) infection. The risk of varicella-associated necrotizing fasciitis should decrease with the implementation of routine childhood immunization against VZV.


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