Are there regional differences in the incidence of skin and upper respiratory tract group A streptococcal (GAS) infections in the US?

Updated: Sep 07, 2018
  • Author: Zartash Zafar Khan, MD, FACP; Chief Editor: Pranatharthi Haran Chandrasekar, MBBS, MD  more...
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Upper respiratory tract infection is most common in the northern regions of the United States, especially during winter and early spring. By contrast, streptococcal skin infections occur most frequently during the summer (or year-round in warm climates), when the skin is exposed and abrasions and insect bites are more likely to occur. Interestingly, unique strains characterized by Erdem and colleagues appear to be predominant in Hawaii, [20] and novel emm types are associated with invasive disease and streptococcal-related sequelae.

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