How is response to treatment evaluated in schistosomiasis (bilharzia)?

Updated: Sep 20, 2018
  • Author: Shadab Hussain Ahmed, MD, AAHIVS, FACP, FIDSA; Chief Editor: Michael Stuart Bronze, MD  more...
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Answer

Response to treatment is evaluated by counting the amount of decrease in egg excretion. In the initial 2 weeks after treatment, the egg count may not decrease, because eggs laid before the treatment require 2 weeks to be shed. Viable eggs can be excreted for 6-8 weeks after treatment.

When measured 5-10 days after treatment, newer tests that measure antigens may help to assess therapeutic response. Persistent circulating antigen and the excretion of eggs indicate residual infection. These patients should be retreated with praziquantel.


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