What is the indication for corticosteroids in the treatment of schistosomiasis (bilharzia)?

Updated: Sep 20, 2018
  • Author: Shadab Hussain Ahmed, MD, AAHIVS, FACP, FIDSA; Chief Editor: Michael Stuart Bronze, MD  more...
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Answer

The symptoms of Katayama syndrome often require administration of corticosteroids to suppress the inflammatory process, but no consensus exists regarding proper antihelminthic treatment. Prednisolone 40mg daily for 5 days can be used for the hypersensitivity reaction. Treatment is essentially supportive.

Persons with CNS involvement should be given corticosteroids to prevent inflammation and edema around eggs. Repeated courses of corticosteroid therapy may be warranted to suppress recrudescent neurologic symptoms.


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