What is the role of biopsy in the diagnosis of schistosomiasis (bilharzia)?

Updated: Jun 11, 2020
  • Author: Shadab Hussain Ahmed, MD, AAHIVS, FACP, FIDSA; Chief Editor: Michael Stuart Bronze, MD  more...
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Biopsy is helpful when stool sample findings are negative or in light infection. Mucosal biopsy is effective for visualizing eggs. Obtain multiple biopsy samples and crush them between slides to increase egg-detecting sensitivity. In one study, 61% of patients had eggs detected on rectal biopsy, whereas only 39% of patients had ova detected in stool. [54]

Liver biopsy has also been used for egg detection and may be appropriate in patients with unclear diagnoses or suspected co-infections.

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