Which medications in the drug class Aldosterone Antagonists, Selective are used in the treatment of Cutibacterium (Propionibacterium) Infections?

Updated: Dec 03, 2019
  • Author: Sajeev Handa, MBBCh, BAO, LRCSI, LRCPI; Chief Editor: John L Brusch, MD, FACP  more...
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Answer

Aldosterone Antagonists, Selective

Aldosterone antagonist may reduce free testosterone levels and compete with androgens binding at the sebaceous gland.

Spironolactone (Aldactone, CaroSpir)

Aldosterone antagonist that competes with testosterone and dihydrotestosterone binding at the receptor in the sebaceous gland. It also reduces free testosterone levels, as more is bound by the increased quantity of SHBG. To treat acne in women may administer 25-200 mg once daily.


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