Which medications in the drug class Estrogens/Progestins are used in the treatment of Cutibacterium (Propionibacterium) Infections?

Updated: Dec 03, 2019
  • Author: Sajeev Handa, MBBCh, BAO, LRCSI, LRCPI; Chief Editor: John L Brusch, MD, FACP  more...
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Answer

Estrogens/Progestins

Hormonal therapies can be used in females with acne, especially those with premenstrual acne flares, who have failed other therapies. Patients may also have signs of hyperandrogenism (eg, hirsutism, irregular menses, menstrual dysfunction). Serum androgen levels may or may not be elevated.

Available options include combination estrogen-progestin oral contraceptive pills, which suppress ovarian androgen production as well as androgen receptor blockers that block the effect of androgens peripherally at the sebaceous gland.

Ethinyl estradiol, drospirenone, and levomefolate (Beyaz, Rajani)

Combination of estrogen and progestin treats acne in adult women. Suppresses ovarian production of androgens.

Ethinyl estradiol and norethindrone (Estrostep Fe, Tilia Fe, Tri-Legest Fe)

Combination of estrogen and progestin treats acne in adult women. Suppresses ovarian production of androgens.

Ethinyl estradiol and norgestimate (Ortho Tri-Cyclen, Tri-Estarylla, TriNessa, Tri-Previfem, Tri-Sprintec)

Combination of estrogen and progestin treats acne in adult women. Suppresses ovarian production of androgens.

Ethinyl estradiol and drospirenone (Yaz, Gianvi, Loryna, Nikki, Vestura)

Combination of estrogen and progestin treats acne in adult women. Suppresses ovarian production of androgens.


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