What is the role of biopsy in the diagnosis of Pott disease (tuberculous [TB] spondylitis)?

Updated: Aug 08, 2019
  • Author: Jose A Hidalgo, MD; Chief Editor: John L Brusch, MD, FACP  more...
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Answer

Percutaneous, CT scan ̶ guided needle biopsy of bone lesions is a safe procedure that also allows therapeutic drainage of large paraspinal abscesses. Obtain a tissue sample for microbiologic and pathologic studies to confirm diagnosis and to isolate organisms for culture and susceptibility. Positive culture yield of percutaneous is 50-83% and appears to be influenced by technical details, such as decontamination of specimens prior to culture. [33]


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