What is the role of isopropyl myristate in the treatment of pediculosis and pthiriasis (lice infestation)?

Updated: Aug 16, 2019
  • Author: Lyn C C Guenther, MD, FRCPC, FAAD; Chief Editor: Michael Stuart Bronze, MD  more...
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Answer

Isopropyl myristate (Resultz) is available in Canada and Europe and received FDA approval for treatment of head lice in 2017, although it is not yet marketed in the United States. It is a non-insecticide–based drug that contains isopropyl myristate, an ingredient commonly used in cosmetics. Its mode of action is a mechanical process that weakens the waxy shell of lice, resulting in internal fluid loss and dehydration. [38] It requires only a 5-minute application time.


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