What is the role of benzyl alcohol lotion 5% (Ulesfia) in the treatment of pediculosis and pthiriasis (lice infestation)?

Updated: Aug 16, 2019
  • Author: Lyn C C Guenther, MD, FRCPC, FAAD; Chief Editor: Michael Stuart Bronze, MD  more...
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Answer

The lotion is given in 2 applications 1 week apart for 10 minutes; it needs to be applied twice because it kills only lice, not nits. Benzyl alcohol lotion may be an easier and safer alternative to lindane and malathion. Because its mechanism of action is physical rather than chemical, development of resistance should not be a concern. In clinical studies, more than 75% of those treated with benzyl alcohol lotion became lice-free. [37]


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