How is nocardiosis prevented?

Updated: Jul 24, 2018
  • Author: George Kurdgelashvili, MD; Chief Editor: Michael Stuart Bronze, MD  more...
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Answer

Although not clearly established, prophylactic therapy for Pneumocystis jiroveci pneumonia (PCP) with TMP-SMX in patients with AIDS whose CD4 count is less than 200 cells/µL probably decreases the likelihood of nocardiosis. (For an excellent discussion of PCP prophylaxis, see the Medscape Reference article Preventing Opportunistic Infections in Patients With HIV.) Similarly, TMP-SMX prophylaxis in solid-organ transplant or hematopoietic stem cell transplant recipients may decrease the likelihood of nocardiosis. However, prophylaxis is not fully effective in either circumstance.


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