Which medications in the drug class Antibiotics are used in the treatment of Mycoplasma Infections (Mycoplasma pneumoniae)?

Updated: Feb 15, 2019
  • Author: Ken B Waites, MD; Chief Editor: Michael Stuart Bronze, MD  more...
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Answer

Antibiotics

Therapy must be comprehensive and cover all likely pathogens in the context of this clinical setting.

Erythromycin (E-Mycin, Ery-Tab, E.E.S.)

Inhibits bacterial growth, possibly by blocking dissociation of peptidyl tRNA from ribosomes, causing RNA-dependent protein synthesis to arrest. For treatment of staphylococcal and streptococcal infections.

In children, age, weight, and severity of infection determine proper dosage. When bid dosing desired, half-total daily dose may be taken q12h. For more severe infections, double the dose.

Clarithromycin (Biaxin, Biaxin XL)

Inhibits bacterial growth, possibly by blocking dissociation of peptidyl tRNA from ribosomes, causing RNA-dependent protein synthesis to arrest.

Azithromycin (Zithromax)

Semisynthetic antibiotic belonging to the macrolide subgroup of azalides and is similar in structure to erythromycin. Inhibits protein synthesis in bacterial cells by binding to the 50S subunit of bacterial ribosomes. Action generally is bacteriostatic but can be bactericidal in high concentrations or against susceptible organisms.

Doxycycline (Vibramycin)

Inhibits protein synthesis and thus bacterial growth by binding to 30S and possibly 50S ribosomal subunits of susceptible bacteria.

Minocycline (Minocin)

Inhibits protein synthesis and thus bacterial growth by binding to 30S and possibly 50S ribosomal subunits of susceptible bacteria.

Levofloxacin (Levaquin)

Inhibits A subunits of DNA gyrase, resulting in inhibition of bacterial DNA replication and transcription.

Moxifloxacin (Avelox)

Inhibits A subunits of DNA gyrase, resulting in inhibition of bacterial DNA replication and transcription.

Gemifloxacin (Factive)

Inhibits DNA gyrase and topoisomerase IV, resulting in inhibition of bacterial DNA replication and transcription.

Telithromycin (Ketek)

Blocks bacterial protein synthesis by binding to domains II and V of 23s rRNA of the 50S ribosomal subunit.


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